CNOT4

CNOT4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1E4U, 1UR6
Identifiers
Aliases	CNOT4, CLONE243, NOT4, NOT4H, CCR4-NOT transcription complex subunit 4
External IDs	OMIM: 604911; MGI: 1859026; HomoloGene: 40870; GeneCards: CNOT4; OMA:CNOT4 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	135,510,127 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	35,110,659 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; Achilles tendon; ; testicle; ; gastrocnemius muscle; ; parietal pleura; ; corpus callosum; ; internal globus pallidus; ; sural nerve; ; endothelial cell; ; muscle of thigh;
	Top expressed in
	genital tubercle; ; Rostral migratory stream; ; tail of embryo; ; zygote; ; saccule; ; primary oocyte; ; secondary oocyte; ; otic placode; ; fossa; ; otic vesicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	ubiquitin-protein transferase activity; protein binding; nucleic acid binding; metal ion binding; transferase activity; RNA binding;
Cellular component	cytosol; cytoplasm; CCR4-NOT complex; nucleus;
Biological process	protein ubiquitination; nuclear-transcribed mRNA poly(A) tail shortening; protein autoubiquitination; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ubiquitin-dependent protein catabolic process; regulation of megakaryocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	4850
	53621
	ENSG00000080802
	ENSMUSG00000038784
	O95628
	Q8BT14
NM_001008225; NM_001190847; NM_001190848; NM_001190849; NM_001190850;
	NM_013316; NM_001393370; NM_001393371; NM_001393372; NM_001393373; NM_001393374; NM_001393375
	NM_001164411; NM_001164412; NM_001164413; NM_001164414; NM_016877
NP_001008226; NP_001177776; NP_001177777; NP_001177778; NP_001177779;
	NP_037448
	NP_001157883; NP_001157884; NP_001157885; NP_001157886; NP_058573
	Wikidata
View/Edit Human	View/Edit Mouse

CCR4-NOT transcription complex, subunit 4 is a protein that in humans is encoded by the CNOT4 gene.