Contactin 2

CNTN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2OM5
Identifiers
Aliases	CNTN2, AXT, FAME5, TAG-1, TAX, TAX1, contactin 2, transient axonal glycoprotein-1
External IDs	OMIM: 190197; MGI: 104518; HomoloGene: 3720; GeneCards: CNTN2; OMA:CNTN2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	205,078,289 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	132,470,994 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; C1 segment; ; corpus callosum; ; internal globus pallidus; ; subthalamic nucleus; ; pars reticulata; ; ventral tegmental area; ; superior vestibular nucleus; ; external globus pallidus; ; Pons;
	Top expressed in
	cerebellar cortex; ; superior frontal gyrus; ; primary visual cortex; ; trigeminal ganglion; ; cerebellar vermis; ; ganglionic eminence; ; lobe of cerebellum; ; central gray substance of midbrain; ; deep cerebellar nuclei; ; pontine nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein self-association; identical protein binding; carbohydrate binding; cell-cell adhesion mediator activity;
Cellular component	membrane; myelin sheath; voltage-gated potassium channel complex; plasma membrane; node of Ranvier; synapse; integral component of plasma membrane; cell surface; axon; soma; anchored component of membrane; neuron projection; juxtaparanode region of axon; anchored component of postsynaptic membrane;
Biological process	clustering of voltage-gated potassium channels; negative regulation of neuron differentiation; central nervous system myelination; receptor internalization; neuron migration; learning; presynaptic membrane organization; regulation of astrocyte differentiation; regulation of axon diameter; cell adhesion; positive regulation of protein processing; establishment of protein localization to juxtaparanode region of axon; positive regulation of adenosine receptor signaling pathway; cerebral cortex GABAergic interneuron migration; regulation of neuronal synaptic plasticity; protein localization to juxtaparanode region of axon; regulation of cell morphogenesis involved in differentiation; neuron projection development; axonal fasciculation; microtubule cytoskeleton organization; adult walking behavior; axon guidance; nervous system development; homophilic cell adhesion via plasma membrane adhesion molecules; dendrite self-avoidance;
	Sources:Amigo / QuickGO
Orthologs
	6900
	21367
	ENSG00000184144
	ENSMUSG00000053024
	Q02246
	Q61330
	NM_005076; NM_001346083
	NM_011531; NM_177129
	NP_001333012; NP_005067
	NP_796103
	Wikidata
View/Edit Human	View/Edit Mouse

Contactin-2 is a protein that in humans is encoded by the CNTN2 gene.