CNTNAP4

CNTNAP4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4NXQ
Identifiers
Aliases	CNTNAP4, CASPR4, contactin associated protein like 4, contactin associated protein family member 4
External IDs	OMIM: 610518; MGI: 2183572; HomoloGene: 24912; GeneCards: CNTNAP4; OMA:CNTNAP4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	76,560,757 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	113,609,349 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; corpus callosum; ; endothelial cell; ; inferior ganglion of vagus nerve; ; Pons; ; substantia nigra; ; subthalamic nucleus; ; Medulla Oblongata; ; Hypothalamus; ; cerebellar hemisphere;
	Top expressed in
	substantia nigra; ; ventral tegmental area; ; pontine nuclei; ; central gray substance of midbrain; ; dorsomedial hypothalamic nucleus; ; cerebellar cortex; ; habenula; ; trigeminal ganglion; ; retinal pigment epithelium; ; lobe of cerebellum;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; cell junction; plasma membrane; dendrite; synapse; presynaptic membrane; membrane; GABA-ergic synapse; integral component of presynaptic membrane;
Biological process	regulation of synaptic transmission, dopaminergic; regulation of grooming behavior; cell adhesion; regulation of synaptic transmission, GABAergic; regulation of synapse organization;
	Sources:Amigo / QuickGO
Orthologs
	85445
	170571
	ENSG00000152910
	ENSMUSG00000031772
	Q9C0A0
	Q99P47
NM_033401; NM_138994; NM_001322178; NM_001322179; NM_001322180;
	NM_001322181; NM_001322187; NM_001322188; NM_001322189; NM_001322190; NM_001322191
	NM_130457
NP_001309107; NP_001309108; NP_001309109; NP_001309110; NP_001309116;
	NP_001309117; NP_001309118; NP_001309119; NP_001309120; NP_207837; NP_620481
	NP_569724
	Wikidata
View/Edit Human	View/Edit Mouse

Contactin-associated protein-like 4 is a protein that in humans is encoded by the CNTNAP4 gene.

This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. Alternative splicing results in two transcript variants encoding different isoforms.