CNTROB

CNTROB
Identifiers
Aliases	CNTROB, LIP8, PP1221, centrobin, centriole duplication and spindle assembly protein
External IDs	OMIM: 611425; MGI: 2443290; HomoloGene: 14205; GeneCards: CNTROB; OMA:CNTROB - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	7,949,920 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,323,775 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; ventricular zone; ; body of uterus; ; ganglionic eminence; ; right lung; ; upper lobe of left lung; ; pancreatic ductal cell; ; canal of the cervix; ; cardiac muscle tissue of right atrium;
	Top expressed in
	superior surface of tongue; ; gallbladder; ; ventricular zone; ; otic vesicle; ; neural layer of retina; ; secondary oocyte; ; spermatocyte; ; zygote; ; thymus; ; primary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; protein domain specific binding;
Cellular component	centriole; centrosome; cytoskeleton; cytoplasm; cytosol;
Biological process	cell cycle; mitotic cytokinetic process; centrosome separation; cell division; centriole replication; regulation of cilium assembly;
	Sources:Amigo / QuickGO
Orthologs
	116840
	216846
	ENSG00000170037
	ENSMUSG00000032782
	Q8N137
	Q8CB62
NM_001037144; NM_053051; NM_001330124; NM_001353202; NM_001353203;
	NM_001353204; NM_001353205; NM_001353206; NM_001353207; NM_001353208; NM_001353209
	NM_172560
NP_001032221; NP_001317053; NP_444279; NP_001340131; NP_001340132;
	NP_001340133; NP_001340134; NP_001340135; NP_001340136; NP_001340137; NP_001340138
	NP_766148
	Wikidata
View/Edit Human	View/Edit Mouse

Centrobin is a protein that in humans is encoded by the CNTROB gene. It is a centriole-associated protein that asymmetrically localizes to the daughter centriole, and is required for centriole duplication and cytokinesis.