COG1

COG1
Identifiers
Aliases	COG1, CDG2G, LDLB, component of oligomeric golgi complex 1
External IDs	OMIM: 606973; MGI: 1333873; HomoloGene: 8411; GeneCards: COG1; OMA:COG1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	73,208,507 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	113,557,880 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; apex of heart; ; right frontal lobe; ; anterior pituitary; ; Brodmann area 9; ; nucleus accumbens; ; prefrontal cortex; ; cingulate gyrus; ; anterior cingulate cortex; ; muscle of thigh;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; motor neuron; ; substantia nigra; ; islet of Langerhans; ; seminiferous tubule; ; Paneth cell; ; right ventricle; ; paraventricular nucleus of hypothalamus; ; submandibular gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	Golgi membrane; Golgi apparatus; membrane; trans-Golgi network membrane; Golgi transport complex;
Biological process	protein transport; endoplasmic reticulum to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; Golgi organization;
	Sources:Amigo / QuickGO
Orthologs
	9382
	16834
	ENSG00000166685
	ENSMUSG00000018661
	Q8WTW3
	Q9Z160
	NM_018714
	NM_013581
	NP_061184
	NP_038609
	Wikidata
View/Edit Human	View/Edit Mouse

Conserved oligomeric Golgi complex subunit 1 is a protein that in humans is encoded by the COG1 gene.

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans-Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.