COG5

COG5
Identifiers
Aliases	COG5, CDG2I, GOLTC1, GTC90, component of oligomeric golgi complex 5
External IDs	OMIM: 606821; MGI: 2145130; HomoloGene: 42221; GeneCards: COG5; OMA:COG5 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	107,564,514 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	31,987,629 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; Achilles tendon; ; bone marrow cells; ; sural nerve; ; tonsil; ; epithelium of colon; ; skeletal muscle tissue; ; endometrium; ; smooth muscle tissue; ; right auricle of heart;
	Top expressed in
	genital tubercle; ; tail of embryo; ; spermatocyte; ; ciliary body; ; spermatid; ; right ventricle; ; dentate gyrus of hippocampal formation granule cell; ; thymus; ; neural layer of retina; ; carotid body;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	cytoplasm; Golgi transport complex; Golgi membrane; cytosol; Golgi apparatus; membrane; nucleoplasm; trans-Golgi network membrane;
Biological process	protein transport; endoplasmic reticulum to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	10466
	238123
	ENSG00000164597; ENSG00000284369
	ENSMUSG00000035933
	Q9UP83
	Q8C0L8
	NM_001161520; NM_006348; NM_181733
	NM_001163126
NP_001154992; NP_006339; NP_859422; NP_001366440; NP_001366441;
	NP_001366442; NP_001366443; NP_001366444; NP_001366445
	NP_001156598
	Wikidata
View/Edit Human	View/Edit Mouse

Conserved oligomeric Golgi complex subunit 5 is a protein that in humans is encoded by the COG5 gene.

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG5 (Ungar et al., 2002).[supplied by OMIM]