Collagen, type VIII, alpha 2

COL8A2
Identifiers
Aliases	COL8A2, FECD, FECD1, PPCD, PPCD2, collagen type VIII alpha 2, collagen type VIII alpha 2 chain
External IDs	OMIM: 120252; MGI: 88464; HomoloGene: 55879; GeneCards: COL8A2; OMA:COL8A2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	36,125,222 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	126,208,123 bp
RNA expression pattern
	Top expressed in
	periodontal fiber; ; tendon of biceps brachii; ; ascending aorta; ; retinal pigment epithelium; ; Descending thoracic aorta; ; right coronary artery; ; popliteal artery; ; tibial arteries; ; Epithelium of choroid plexus; ; cartilage tissue;
	Top expressed in
	Epithelium of choroid plexus; ; calvaria; ; retinal pigment epithelium; ; cornea; ; condyle; ; lumbar spinal ganglion; ; efferent ductule; ; fossa; ; vas deferens; ; iris;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein-macromolecule adaptor activity; extracellular matrix structural constituent; extracellular matrix structural constituent conferring tensile strength; protein binding;
Cellular component	extracellular matrix; extracellular region; basement membrane; collagen; endoplasmic reticulum lumen; extracellular space; collagen-containing extracellular matrix;
Biological process	collagen catabolic process; extracellular matrix organization; epithelial cell proliferation; cell adhesion; camera-type eye morphogenesis; angiogenesis; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	1296
	329941
	ENSG00000171812
	ENSMUSG00000056174
	P25067; Q4VAQ0
	P25318
	NM_001294347; NM_005202
	NM_199473
	NP_001281276; NP_005193
	NP_955767
	Wikidata
View/Edit Human	View/Edit Mouse

Collagen alpha-2(VIII) chain is a protein that in humans is encoded by the COL8A2 gene. Mutations of the gene are linked to posterior polymorphous dystrophy type 2.