Collagen, type IX, alpha 2

COL9A2
Identifiers
Aliases	COL9A2, DJ39G22.4, EDM2, MED, STL5, collagen type IX alpha 2, collagen type IX alpha 2 chain
External IDs	OMIM: 120260; MGI: 88466; HomoloGene: 37535; GeneCards: COL9A2; OMA:COL9A2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	40,317,813 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	120,912,519 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; tibia; ; anterior pituitary; ; cartilage tissue; ; ganglionic eminence; ; Amygdala; ; putamen; ; caudate nucleus; ; Hypothalamus; ; nucleus accumbens;
	Top expressed in
	vestibular sensory epithelium; ; saccule; ; utricle; ; otic vesicle; ; molar; ; human vertebral column; ; Ileal epithelium; ; lens; ; axial skeleton; ; cochlea;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	extracellular matrix structural constituent conferring tensile strength; extracellular matrix structural constituent;
Cellular component	extracellular region; endoplasmic reticulum lumen; collagen; collagen type IX trimer; basement membrane; extracellular space; extracellular matrix; collagen-containing extracellular matrix;
Biological process	skeletal system development; extracellular matrix organization;
	Sources:Amigo / QuickGO
Orthologs
	1298
	12840
	ENSG00000049089
	ENSMUSG00000028626
	Q14055
	Q07643
	NM_001852
	NM_007741
	NP_001843
	NP_031767
	Wikidata
View/Edit Human	View/Edit Mouse

Collagen alpha-2(IX) chain is a protein that in humans is encoded by the COL9A2 gene.

This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia.