Coenzyme Q5, methyltransferase

2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase
2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase
Identifiers
EC no.	2.1.1.201
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
PMC
Search
PMC	articles
PubMed	articles
NCBI	proteins

COQ5
Identifiers
Aliases	COQ5, coenzyme Q5, methyltransferase, COQ10D9
External IDs	OMIM: 616359; MGI: 1098643; HomoloGene: 6559; GeneCards: COQ5; OMA:COQ5 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	120,534,434 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	115,435,031 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; skeletal muscle tissue; ; apex of heart; ; right lobe of liver; ; mucosa of transverse colon; ; left ventricle; ; right adrenal cortex; ; islet of Langerhans; ; gonad;
	Top expressed in
	muscle of thigh; ; Paneth cell; ; digastric muscle; ; sternocleidomastoid muscle; ; interventricular septum; ; motor neuron; ; genital tubercle; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; temporal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	methyltransferase activity; transferase activity; protein binding; 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity; 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity;
Cellular component	membrane; mitochondrion; mitochondrial inner membrane; mitochondrial matrix; protein-containing complex; extrinsic component of mitochondrial inner membrane;
Biological process	ubiquinone biosynthetic process; methylation;
	Sources:Amigo / QuickGO
Orthologs
	84274
	52064
	ENSG00000110871
	ENSMUSG00000041733
	Q5HYK3
	Q9CXI0
	NM_032314
	NM_026504
	NP_115690
	NP_080780
	Wikidata
View/Edit Human	View/Edit Mouse

Coenzyme Q5, methyltransferase, more commonly known as COQ5, is an enzyme involved in the electron transport chain. COQ5 is located within the mitochondrial matrix and is a part of the biosynthesis of ubiquinone.