CORIN

CORIN
Identifiers
Aliases	CORIN, ATC2, CRN, Lrp4, PEE5, TMPRSS10, corin, serine peptidase
External IDs	OMIM: 605236; MGI: 1349451; HomoloGene: 4804; GeneCards: CORIN; OMA:CORIN - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	47,838,106 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	72,661,816 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; right ventricle; ; right auricle of heart; ; myocardium of left ventricle; ; apex of heart; ; decidua; ; skin of thigh; ; human penis; ; skin of arm; ; stromal cell of endometrium;
	Top expressed in
	myocardium of ventricle; ; atrium; ; right ventricle; ; atrioventricular valve; ; cardiac muscle tissue of left ventricle; ; umbilical cord; ; skin of external ear; ; interventricular septum; ; hair follicle; ; vestibular sensory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity;
Cellular component	integral component of membrane; cell surface; integral component of plasma membrane; extracellular region; membrane; plasma membrane; actin cytoskeleton; nuclear body;
Biological process	regulation of cardiac conduction; regulation of renal sodium excretion; proteolysis; regulation of blood pressure; regulation of systemic arterial blood pressure by atrial natriuretic peptide; peptide hormone processing; female pregnancy;
	Sources:Amigo / QuickGO
Orthologs
	10699
	53419
	ENSG00000145244
	ENSMUSG00000005220
	Q9Y5Q5
	Q9Z319
	NM_006587; NM_001278585; NM_001278586
	NM_001122756; NM_016869
	NP_001265514; NP_001265515; NP_006578
	NP_001116228; NP_058565
	Wikidata
View/Edit Human	View/Edit Mouse

Corin, also called atrial natriuretic peptide-converting enzyme, is a protein that in humans is encoded by the CORIN gene.