COX6B1

COX6B1
Identifiers
Aliases	COX6B1, COX6B, COXG, COXVIb1, cytochrome c oxidase subunit 6B1, MC4DN7
External IDs	OMIM: 124089; MGI: 107460; HomoloGene: 39658; GeneCards: COX6B1; OMA:COX6B1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	35,658,782 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; left ventricle; ; right ventricle; ; right auricle of heart; ; mucosa of transverse colon; ; muscle of thigh; ; rectum; ; triceps brachii muscle; ; gastrocnemius muscle; ; Brodmann area 9;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytochrome-c oxidase activity; protein binding;
Cellular component	mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; respiratory chain complex IV;
Biological process	substantia nigra development; mitochondrial electron transport, cytochrome c to oxygen; proton transmembrane transport; electron transport chain;
	Sources:Amigo / QuickGO
Orthologs
	1340
	110323
	ENSG00000126267
	ENSMUSG00000036751
	P14854
	P56391
	NM_001863
	NM_025628
	NP_001854
	NP_079904
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome c oxidase subunit 6B1 is an enzyme that in humans is encoded by the COX6B1 gene. Cytochrome c oxidase 6B1 is a subunit of the cytochrome c oxidase complex, also known as Complex IV, the last enzyme in the mitochondrial electron transport chain. Mutations of the COX6B1 gene are associated with severe infantile encephalomyopathy and mitochondrial complex IV deficiency (MT-C4D).