Carboxypeptidase A2

CPA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AYE, 1DTD, 1O6X
Identifiers
Aliases	CPA2, carboxypeptidase A2
External IDs	OMIM: 600688; MGI: 3617840; HomoloGene: 37541; GeneCards: CPA2; OMA:CPA2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	130,289,798 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	30,564,475 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; islet of Langerhans; ; pancreatic epithelial cell; ; body of stomach; ; beta cell; ; duodenum; ; testicle; ; C1 segment; ; fundus; ; jejunal mucosa;
	Top expressed in
	pyloric antrum; ; islet of Langerhans; ; embryo; ; duodenum; ; retinal pigment epithelium; ; genital tubercle; ; saccule; ; sexually immature organism; ; migratory enteric neural crest cell; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	carboxypeptidase activity; metallopeptidase activity; zinc ion binding; peptidase activity; hydrolase activity; metallocarboxypeptidase activity; metal ion binding;
Cellular component	extracellular region; vacuole; extracellular space;
Biological process	proteolysis; protein catabolic process in the vacuole;
	Sources:Amigo / QuickGO
Orthologs
	1358
	232680
	ENSG00000158516
	ENSMUSG00000071553
	P48052
	Q504N0
	NM_001869
	NM_001024698
	NP_001860
	NP_001019869
	Wikidata
View/Edit Human	View/Edit Mouse

Carboxypeptidase A2 is an enzyme that in humans is encoded by the CPA2 gene.

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues