CPA5

CPA5
Identifiers
Aliases	CPA5, carboxypeptidase A5
External IDs	OMIM: 609561; MGI: 1921899; HomoloGene: 62246; GeneCards: CPA5; OMA:CPA5 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	130,368,730 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	30,631,744 bp
RNA expression pattern
	Top expressed in
	testicle; ; right testis; ; left testis; ; sperm; ; gonad; ; lymph node; ; body of pancreas; ; pituitary gland; ; anterior pituitary; ; spleen;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; embryo; ; embryo; ; morula; ; yolk sac; ; genital tubercle; ; islet of Langerhans; ; trachea;
	More reference expression data
	n/a
Gene ontology
Molecular function	carboxypeptidase activity; zinc ion binding; peptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; metallocarboxypeptidase activity;
Cellular component	extracellular region; extracellular space;
Biological process	proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	93979
	74649
	ENSG00000158525
	ENSMUSG00000029788
	Q8WXQ8
	Q8R4H4
	NM_001127441; NM_001127442; NM_080385; NM_001318223
	NM_144537
	NP_001120913; NP_001120914; NP_001305152; NP_525124
	NP_653120
	Wikidata
View/Edit Human	View/Edit Mouse

Carboxypeptidase A5 is an enzyme that in humans is encoded by the CPA5 gene.

Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002).[supplied by OMIM]