CPLX1

CPLX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3RK3, 3RL0
Identifiers
Aliases	CPLX1, CPX-I, CPX1, complexin 1, EIEE63, DEE63
External IDs	OMIM: 605032; MGI: 104727; HomoloGene: 21324; GeneCards: CPLX1; OMA:CPLX1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	826,129 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	108,697,890 bp
RNA expression pattern
	Top expressed in
	lateral nuclear group of thalamus; ; external globus pallidus; ; postcentral gyrus; ; Pons; ; superior frontal gyrus; ; right frontal lobe; ; putamen; ; primary visual cortex; ; right hemisphere of cerebellum; ; caudate nucleus;
	Top expressed in
	motor neuron; ; substantia nigra; ; facial motor nucleus; ; pontine nuclei; ; lateral geniculate nucleus; ; medial vestibular nucleus; ; habenula; ; anterior horn of spinal cord; ; medial geniculate nucleus; ; deep cerebellar nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	syntaxin-1 binding; neurotransmitter transmembrane transporter activity; syntaxin binding; SNARE binding; protein binding;
Cellular component	cytoplasm; cytosol; synapse; synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex; synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; soma; dendrite; SNARE complex; protein-containing complex; presynapse; calyx of Held; Schaffer collateral - CA1 synapse; postsynapse; glutamatergic synapse; terminal bouton;
Biological process	synaptic vesicle exocytosis; insulin secretion; regulation of exocytosis; neurotransmitter transport; exocytosis; chemical synaptic transmission; regulation of synaptic vesicle fusion to presynaptic active zone membrane; exocytic insertion of neurotransmitter receptor to postsynaptic membrane; vesicle-mediated transport in synapse; regulation of neurotransmitter secretion; neurotransmitter secretion; glutamate secretion;
	Sources:Amigo / QuickGO
Orthologs
	10815
	12889
	ENSG00000168993
	ENSMUSG00000033615
	O14810
	P63040
	NM_006651
	NM_007756
	NP_006642
	NP_031782
	Wikidata
View/Edit Human	View/Edit Mouse

Complexin-1 is a protein that in humans is encoded by the CPLX1 gene.