CPNE6

CPNE6
Identifiers
Aliases	CPNE6, copine 6
External IDs	OMIM: 605688; MGI: 1334445; HomoloGene: 81815; GeneCards: CPNE6; OMA:CPNE6 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	24,078,100 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,754,888 bp
RNA expression pattern
	Top expressed in
	temporal lobe; ; Amygdala; ; right hemisphere of cerebellum; ; hippocampus proper; ; superior frontal gyrus; ; right frontal lobe; ; nucleus accumbens; ; anterior cingulate cortex; ; prefrontal cortex; ; putamen;
	Top expressed in
	CA3 field; ; subiculum; ; dentate gyrus; ; dentate gyrus of hippocampal formation granule cell; ; entorhinal cortex; ; perirhinal cortex; ; hippocampus proper; ; anterior amygdaloid area; ; Region I of hippocampus proper; ; facial motor nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; transporter activity; phosphatidylserine binding; protein binding; calcium-dependent phospholipid binding;
Cellular component	cytoplasm; endosome; perikaryon; cell projection; membrane; clathrin-coated endocytic vesicle; plasma membrane; axon; dendrite; extracellular exosome; cytoplasmic vesicle; clathrin-coated vesicle;
Biological process	cellular response to calcium ion; cell differentiation; lipid metabolism; nervous system development; glycerophospholipid biosynthetic process; positive regulation of dendrite extension; vesicle-mediated transport; chemical synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	9362
	12891
	ENSG00000100884
	ENSMUSG00000022212
	O95741
	Q9Z140
	NM_001280558; NM_006032
	NM_001136057; NM_001146183; NM_009947; NM_001360193
	NP_001267487; NP_006023
	NP_001129529; NP_001139655; NP_034077; NP_001347122
	Wikidata
View/Edit Human	View/Edit Mouse

Copine-6 is a protein that in humans is encoded by the CPNE6 gene.

This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.