CPSF6

CPSF6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3P5T, 3P6Y, 3Q2S, 3Q2T, 4B4N, 4U0A, 4U0B, 4WYM
Identifiers
Aliases	CPSF6, CFIM, CFIM68, HPBRII-4, HPBRII-7, cleavage and polyadenylation specific factor 6, CFIM72
External IDs	OMIM: 604979; MGI: 1913948; HomoloGene: 134126; GeneCards: CPSF6; OMA:CPSF6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	69,274,358 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	117,215,920 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; bone marrow cells; ; Achilles tendon; ; ventricular zone; ; tonsil; ; left ovary; ; right ovary; ; appendix; ; sural nerve; ; endometrium;
	Top expressed in
	superior cervical ganglion; ; hand; ; otolith organ; ; utricle; ; mandibular prominence; ; cumulus cell; ; trigeminal ganglion; ; maxillary prominence; ; abdominal wall; ; ganglionic eminence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; mRNA binding; RNA binding; nucleic acid binding; ribosomal large subunit binding; exon-exon junction complex binding;
Cellular component	paraspeckles; membrane; nucleus; nucleoplasm; nuclear speck; mRNA cleavage factor complex; perichromatin fibrils; cytoplasm; mRNA cleavage and polyadenylation specificity factor complex; interchromatin granule; ribonucleoprotein complex;
Biological process	mRNA polyadenylation; mRNA processing; protein tetramerization; positive regulation of RNA export from nucleus; protein heterotetramerization; pre-mRNA cleavage required for polyadenylation; mRNA alternative polyadenylation; messenger ribonucleoprotein complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	11052
	432508
	ENSG00000111605
	ENSMUSG00000055531
	Q16630
	Q6NVF9
	NM_001300947; NM_007007
	NM_001013391; NM_001310609
	NP_001287876; NP_008938
	NP_001013409; NP_001297538
	Wikidata
View/Edit Human	View/Edit Mouse

Cleavage and polyadenylation specificity factor subunit 6 is a protein that in humans is encoded by the CPSF6 gene.