CRELD2

Cysteine-rich with EGF-like domain protein 2 is a protein that in humans is encoded by the CRELD2 gene found on chromosome 22q13. It is a known homolog of CRELD1. CRELD2's identifying feature is a tryptophan-aspartic acid domain. It is a multifunctional glycoprotein that is approximately 60 kilodaltons and can reside in the endoplasmic reticulum (ER) or Golgi apparatus and be secreted spontaneously. It is implicated in numerous ER stress-related diseases including chronic liver disease, cardiovascular disease, kidney disease, and cancer.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.