CRIP2

CRIP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CU8
Identifiers
Aliases	CRIP2, CRIP, CRP2, ESP1, cysteine rich protein 2
External IDs	OMIM: 601183; MGI: 1915587; HomoloGene: 135666; GeneCards: CRIP2; OMA:CRIP2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	105,480,162 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	113,109,126 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right auricle of heart; ; right coronary artery; ; popliteal artery; ; tibial arteries; ; Descending thoracic aorta; ; ascending aorta; ; left coronary artery; ; right uterine tube; ; left ventricle;
	Top expressed in
	ankle joint; ; right ventricle; ; right lung; ; right lung lobe; ; left lung; ; gastrula; ; interventricular septum; ; endothelial cell of lymphatic vessel; ; lip; ; atrium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; zinc ion binding; protein binding;
Cellular component	cell cortex;
Biological process	positive regulation of cell population proliferation; hemopoiesis;
	Sources:Amigo / QuickGO
Orthologs
	1397
	68337
	ENSG00000182809
	ENSMUSG00000006356
	P52943
	Q9DCT8
	NM_001270837; NM_001270841; NM_001312
	NM_024223; NM_001347443
	NP_001257766; NP_001257770; NP_001303
	NP_001334372; NP_077185
	Wikidata
View/Edit Human	View/Edit Mouse

Cysteine-rich protein 2 is a protein that in humans is encoded by the CRIP2 gene.

CRIP2 and the closely related CRIP1 are cysteine-rich proteins containing two LIM domains. They are highly expressed during cardiovascular development and act to bridge serum response factor and GATA proteins and stimulate smooth muscle target genes.