CRLF1

CRLF1
Identifiers
Aliases	CRLF1, CISS, CISS1, CLF, CLF-1, NR6, zcytor5, cytokine receptor like factor 1
External IDs	OMIM: 604237; MGI: 1340030; HomoloGene: 3489; GeneCards: CRLF1; OMA:CRLF1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	18,607,741 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	70,956,731 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; popliteal artery; ; tibial arteries; ; left coronary artery; ; thoracic aorta; ; ascending aorta; ; right lobe of thyroid gland; ; decidua; ; left lobe of thyroid gland; ; Descending thoracic aorta;
	Top expressed in
	stroma of bone marrow; ; seminiferous tubule; ; corneal stroma; ; maxillary prominence; ; lower lip; ; submandibular gland; ; upper lip; ; hand; ; endothelial cell of lymphatic vessel; ; calvaria;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein heterodimerization activity; ciliary neurotrophic factor receptor binding; cytokine activity; protein binding; cytokine binding; cytokine receptor activity;
Cellular component	extracellular region; CRLF-CLCF1 complex; extracellular space; cytosol; external side of plasma membrane; receptor complex;
Biological process	negative regulation of neuron apoptotic process; ureteric bud development; positive regulation of cell population proliferation; negative regulation of motor neuron apoptotic process; positive regulation of tyrosine phosphorylation of STAT protein; regulation of signaling receptor activity; cytokine-mediated signaling pathway; interleukin-27-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9244
	12931
	ENSG00000006016
	ENSMUSG00000007888
	O75462
	Q9JM58
	NM_004750
NM_018827; NM_001378799; NM_001378800; NM_001378801; NM_001378802;
	NM_001378803
	NP_004741
NP_061297; NP_001365728; NP_001365729; NP_001365730; NP_001365731;
	NP_001365732
	Wikidata
View/Edit Human	View/Edit Mouse

Cytokine receptor-like factor 1 is a protein that in humans is encoded by the CRLF1 gene.