CRTC3

CRTC3
Identifiers
Aliases	CRTC3, TORC-3, TORC3, CREB regulated transcription coactivator 3
External IDs	OMIM: 608986; MGI: 1917711; HomoloGene: 11248; GeneCards: CRTC3; OMA:CRTC3 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	90,645,345 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	80,338,625 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; saphenous vein; ; parotid gland; ; visceral pleura; ; urethra; ; inferior olivary nucleus; ; parietal pleura; ; dorsal motor nucleus of vagus nerve; ; nipple; ; popliteal artery;
	Top expressed in
	zygote; ; internal carotid artery; ; external carotid artery; ; sciatic nerve; ; Gonadal ridge; ; secondary oocyte; ; Rostral migratory stream; ; genital tubercle; ; lacrimal gland; ; mesenteric lymph nodes;
	More reference expression data
	n/a
Gene ontology
Molecular function	cAMP response element binding protein binding; protein binding;
Cellular component	nucleus; nucleoplasm; cytoplasm; cytosol;
Biological process	energy homeostasis; macrophage activation; positive regulation of CREB transcription factor activity; viral process; negative regulation of lipid catabolic process; regulation of transcription, DNA-templated; protein homotetramerization; negative regulation of cAMP-mediated signaling; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	64784
	70461
	ENSG00000140577
	ENSMUSG00000030527
	Q6UUV7
	Q91X84
	NM_001042574; NM_022769
	NM_173863
	NP_001036039; NP_073606
	NP_776288
	Wikidata
View/Edit Human	View/Edit Mouse

CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene.

This gene has been shown to be linked to weight gain.