CRX (gene)

CRX
Identifiers
Aliases	CRX, CORD2, CRD, LCA7, OTX3, cone-rod homeobox
External IDs	OMIM: 602225; MGI: 1194883; HomoloGene: 467; GeneCards: CRX; OMA:CRX - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	47,843,330 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	15,613,893 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; gonad; ; testicle; ; Epithelium of choroid plexus; ; right lobe of liver; ; granulocyte; ; monocyte; ; upper respiratory tract; ; gallbladder; ; mucosa of nose;
	Top expressed in
	neural layer of retina; ; outer nuclear layer; ; inner nuclear layer; ; pineal gland; ; epithelium of lens; ; retinal pigment epithelium; ; photoreceptor layer of retina; ; Ileal epithelium; ; lumbar spinal ganglion; ; corneal stroma;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific; DNA binding; leucine zipper domain binding; protein binding; sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	circadian rhythm; nervous system development; animal organ morphogenesis; positive regulation of transcription by RNA polymerase II; response to stimulus; positive regulation of photoreceptor cell differentiation; transcription, DNA-templated; multicellular organism development; cell differentiation; regulation of transcription, DNA-templated; visual perception; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	1406
	12951
	ENSG00000105392
	ENSMUSG00000041578
	O43186
	O54751
	NM_000554
	NM_001113330; NM_007770
	NP_000545
	NP_001106801; NP_031796
	Wikidata
View/Edit Human	View/Edit Mouse

Cone-rod homeobox protein is a protein that in humans is encoded by the CRX gene.