CRYM

CRYM
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2I99
Identifiers
Aliases	CRYM, DFNA40, THBP, crystallin mu
External IDs	OMIM: 123740; MGI: 102675; HomoloGene: 1424; GeneCards: CRYM; OMA:CRYM - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	21,303,083 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	119,801,334 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; frontal pole; ; paraflocculus of cerebellum; ; right hemisphere of cerebellum; ; Brodmann area 10; ; orbitofrontal cortex; ; apex of heart; ; nucleus accumbens; ; Brodmann area 9; ; right frontal lobe;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; hippocampus proper; ; olfactory tubercle; ; nucleus accumbens; ; subiculum; ; lip; ; dorsal striatum; ; Region I of hippocampus proper; ; superior frontal gyrus; ; CA3 field;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; hormone binding; protein binding; protein homodimerization activity; transcription corepressor activity; NADP binding; thyroid hormone binding; thiomorpholine-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor;
Cellular component	cytoplasm; extracellular exosome; mitochondrion; nucleus; peroxisomal matrix; cytosol;
Biological process	thyroid hormone transport; negative regulation of transcription by RNA polymerase II; hearing; lysine catabolic process; thyroid hormone metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1428
	12971
	ENSG00000103316
	ENSMUSG00000030905
	Q14894
	O54983
	NM_001014444; NM_001888; NM_001376256
	NM_016669
	NP_001879; NP_001363185
	NP_057878
	Wikidata
View/Edit Human	View/Edit Mouse

Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.