CSNK1D

CSNK1D
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3UYS, 3UYT, 3UZP, 4HGT, 4HNF, 4KB8, 4KBA, 4KBC, 4KBK, 4TW9, 4TWC, 4TN6, 5IH6, 5IH5, 5IH4
Identifiers
Aliases	CSNK1D, ASPS, CKIdelta, FASPS2, HCKID, casein kinase 1 delta, CKId, CKI-delta
External IDs	OMIM: 600864; MGI: 1355272; HomoloGene: 74841; GeneCards: CSNK1D; OMA:CSNK1D - orthologs
EC number	2.7.11.26
Gene location (Human)
Chr.	Chromosome 17 (human)
End	82,273,700 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,882,156 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; granulocyte; ; left uterine tube; ; anterior pituitary; ; left lobe of thyroid gland; ; minor salivary glands; ; gastric mucosa; ; right lung; ; right lobe of thyroid gland;
	Top expressed in
	Paneth cell; ; fossa; ; condyle; ; retinal pigment epithelium; ; vestibular membrane of cochlear duct; ; ciliary body; ; motor neuron; ; renal corpuscle; ; trigeminal ganglion; ; endothelial cell of lymphatic vessel;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; peptide binding; kinase activity; tau-protein kinase activity; ATP binding; protein serine/threonine kinase activity; cadherin binding; protein binding;
Cellular component	cytoplasm; cytosol; Golgi apparatus; membrane; plasma membrane; spindle; microtubule organizing center; spindle microtubule; perinuclear region of cytoplasm; neuron projection; endoplasmic reticulum-Golgi intermediate compartment membrane; cytoskeleton; Golgi membrane; nucleus; centrosome; nucleoplasm;
Biological process	cellular response to nerve growth factor stimulus; positive regulation of protein phosphorylation; Golgi organization; phosphorylation; rhythmic process; positive regulation of canonical Wnt signaling pathway; circadian regulation of gene expression; spindle assembly; positive regulation of Wnt signaling pathway; COPII vesicle coating; G2/M transition of mitotic cell cycle; regulation of circadian rhythm; peptidyl-serine phosphorylation; protein localization to cilium; protein localization to Golgi apparatus; protein localization to centrosome; positive regulation of non-canonical Wnt signaling pathway; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; microtubule nucleation; regulation of cell shape; endocytosis; rRNA processing; Wnt signaling pathway; ciliary basal body-plasma membrane docking; positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation; non-motile cilium assembly; protein phosphorylation; regulation of G2/M transition of mitotic cell cycle; peptidyl-threonine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	1453
	104318
	ENSG00000141551
	ENSMUSG00000025162
	P48730
	Q9DC28
	NM_001893; NM_139062; NM_001363749
	NM_027874; NM_139059
	NP_001884; NP_620693; NP_001350678
	NP_082150; NP_620690
	Wikidata
View/Edit Human	View/Edit Mouse

Casein kinase I isoform delta also known as CKI-delta or CK1δ is an enzyme that in humans is encoded by the gene CSNK1D, which is located on chromosome 17 (17q25.3). It is a member of the CK1 (formerly named casein kinase 1) family of serine/threonine specific eukaryotic protein kinases encompassing seven distinct isoforms (CK1α, γ1-3, δ, ε) as well as various post-transcriptionally processed splice variants (transcription variants, TVs) in mammalians. Meanwhile, CK1δ homologous proteins have been isolated from organisms like yeast, basidiomycetes, plants, algae, and protozoa.