CSPG4

CSPG4
Identifiers
Aliases	CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2, chondroitin sulfate proteoglycan 4, CSPG4A
External IDs	OMIM: 601172; MGI: 2153093; HomoloGene: 20445; GeneCards: CSPG4; OMA:CSPG4 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	75,712,848 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	56,807,154 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; cartilage tissue; ; tibia; ; popliteal artery; ; tibial arteries; ; right coronary artery; ; Descending thoracic aorta; ; ascending aorta; ; left coronary artery; ; muscle layer of sigmoid colon;
	Top expressed in
	ascending aorta; ; tunica media of zone of aorta; ; internal carotid artery; ; aortic valve; ; fossa; ; condyle; ; external carotid artery; ; phalanx of foot; ; phalanx of third toe; ; phalanx of fourth toe;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; protein kinase binding;
Cellular component	integral component of membrane; cell projection; membrane; focal adhesion; plasma membrane; integral component of plasma membrane; extracellular region; cell surface; lysosomal lumen; apical plasma membrane; Golgi lumen; extracellular exosome; lamellipodium membrane; extracellular matrix; collagen-containing extracellular matrix;
Biological process	glycosaminoglycan metabolic process; cell differentiation; intracellular signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway; chondroitin sulfate biosynthetic process; multicellular organism development; angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; chondroitin sulfate catabolic process; dermatan sulfate biosynthetic process; cell population proliferation; tissue remodeling; signal transduction; glial cell migration;
	Sources:Amigo / QuickGO
Orthologs
	1464
	121021
	ENSG00000173546
	ENSMUSG00000032911
	Q6UVK1
	Q8VHY0
	NM_001897
	NM_139001
	NP_001888
	NP_620570
	Wikidata
View/Edit Human	View/Edit Mouse

Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that in humans is encoded by the CSPG4 gene.