CSTF1

CSTF1
Identifiers
Aliases	CSTF1, CstF-50, CstFp50, cleavage stimulation factor subunit 1
External IDs	OMIM: 600369; MGI: 1914587; HomoloGene: 1012; GeneCards: CSTF1; OMA:CSTF1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	56,406,362 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	172,224,368 bp
RNA expression pattern
	Top expressed in
	testicle; ; secondary oocyte; ; Achilles tendon; ; gonad; ; islet of Langerhans; ; stromal cell of endometrium; ; ventricular zone; ; rectum; ; granulocyte; ; body of pancreas;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; yolk sac; ; epiblast; ; ventricular zone; ; secondary oocyte; ; Ileal epithelium; ; tail of embryo; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	nucleus; nucleoplasm; mRNA cleavage stimulating factor complex;
Biological process	mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; mRNA processing; mRNA 3'-end processing;
	Sources:Amigo / QuickGO
Orthologs
	1477
	67337
	ENSG00000101138
	ENSMUSG00000027498
	Q05048
	Q99LC2
	NM_001033521; NM_001033522; NM_001324
	NM_024199
	NP_001028693; NP_001028694; NP_001315
	NP_077161
	Wikidata
View/Edit Human	View/Edit Mouse

Cleavage stimulation factor 50 kDa subunit is a protein that in humans is encoded by the CSTF1 gene.

This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.