CTBP1

CTBP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1MX3, 4LCE, 4U6Q
Identifiers
Aliases	CTBP1, C-terminal binding protein 1, BARS, HADDTS
External IDs	OMIM: 602618; MGI: 1201685; HomoloGene: 1015; GeneCards: CTBP1; OMA:CTBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	1,249,953 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	33,432,338 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; right hemisphere of cerebellum; ; internal globus pallidus; ; anterior pituitary; ; postcentral gyrus; ; buccal mucosa cell; ; body of pancreas; ; Region I of hippocampus proper; ; stromal cell of endometrium; ; prefrontal cortex;
	Top expressed in
	renal corpuscle; ; medullary collecting duct; ; ventricular zone; ; tail of embryo; ; fetal liver hematopoietic progenitor cell; ; ganglionic eminence; ; Rostral migratory stream; ; Paneth cell; ; dentate gyrus of hippocampal formation granule cell; ; medial ganglionic eminence;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; transcription corepressor activity; protein domain specific binding; DNA-binding transcription factor activity; NAD binding; transcription factor binding; protein C-terminus binding; protein binding; oxidoreductase activity; identical protein binding; hydroxypyruvate reductase activity; glyoxylate reductase (NADP+) activity; protein homodimerization activity;
Cellular component	cytoplasm; transcription regulator complex; transcription repressor complex; nucleoplasm; nucleus; cytosol; presynaptic active zone cytoplasmic component; glutamatergic synapse; GABA-ergic synapse;
Biological process	positive regulation of histone deacetylation; cell differentiation; regulation of transcription, DNA-templated; viral genome replication; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; regulation of cell cycle; negative regulation of histone H4 acetylation; protein phosphorylation; white fat cell differentiation; metabolism; viral process; negative regulation of transcription, DNA-templated; negative regulation of histone acetylation; negative regulation of cell population proliferation;
	Sources:Amigo / QuickGO
Orthologs
	1487
	13016
	ENSG00000159692
	ENSMUSG00000037373
	Q13363
	O88712
NM_001012614; NM_001328; NM_001377186; NM_001377187; NM_001377188;
	NM_001377189; NM_001377190; NM_001377191; NM_001377192; NM_001377193
	NM_001198859; NM_001198860; NM_001198861; NM_013502; NM_001310535
NP_001012632; NP_001319; NP_001364115; NP_001364116; NP_001364117;
	NP_001364118; NP_001364119; NP_001364120; NP_001364121; NP_001364122
	NP_001185788; NP_001185789; NP_001185790; NP_001297464; NP_038530
	Wikidata
View/Edit Human	View/Edit Mouse

C-terminal-binding protein 1 also known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene. CtBP1 is one of two CtBP proteins, the other protein being CtBP2.