CTDP1

CTDP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1J2X, 1ONV, 2K7L
Identifiers
Aliases	CTDP1, CCFDN, FCP1, CTD phosphatase subunit 1
External IDs	OMIM: 604927; MGI: 1926953; HomoloGene: 31254; GeneCards: CTDP1; OMA:CTDP1 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	79,754,503 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	80,512,910 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; skin of leg; ; oocyte; ; granulocyte; ; blood; ; mucosa of transverse colon; ; skin of abdomen; ; secondary oocyte; ; monocyte;
	Top expressed in
	spermatid; ; otic vesicle; ; epiblast; ; fetal liver hematopoietic progenitor cell; ; hair follicle; ; seminiferous tubule; ; Gonadal ridge; ; primitive streak; ; somite; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II CTD heptapeptide repeat phosphatase activity; protein binding; hydrolase activity; phosphoprotein phosphatase activity; TFIIF-class transcription factor complex binding; Tat protein binding;
Cellular component	cytoplasm; centrosome; spindle pole; RNA polymerase II, holoenzyme; spindle; microtubule organizing center; midbody; spindle midzone; cytoskeleton; nucleus; nucleoplasm; intracellular membrane-bounded organelle; protein-containing complex; actin cytoskeleton; nuclear speck;
Biological process	transcription elongation from RNA polymerase II promoter; protein dephosphorylation; exit from mitosis; transcription by RNA polymerase II; cell division; negative regulation of cell growth involved in cardiac muscle cell development; dephosphorylation of RNA polymerase II C-terminal domain; cell cycle; positive regulation by host of viral transcription; positive regulation of viral transcription;
	Sources:Amigo / QuickGO
Orthologs
	9150
	67655
	ENSG00000282752; ENSG00000060069
	ENSMUSG00000033323
	Q9Y5B0
	Q7TSG2
	NM_001202504; NM_004715; NM_048368; NM_001318511
	NM_026295
	NP_001189433; NP_001305440; NP_004706; NP_430255
	NP_080571
	Wikidata
View/Edit Human	View/Edit Mouse

RNA polymerase II subunit A C-terminal domain phosphatase is an enzyme that in humans is encoded by the CTDP1 gene.

This gene encodes a protein which interacts with the carboxy-terminus of transcription initiation factor TFIIF, a transcription factor which regulates elongation as well as initiation by RNA polymerase II. The protein may also represent a component of an RNA polymerase II holoenzyme complex. Alternative splicing of this gene results in two transcript variants encoding 2 different isoforms.