CUL5

CUL5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3DPL, 3DQV, 4JGH, 4N9F
Identifiers
Aliases	CUL5, VACM-1, VACM1, cullin 5, CUL-5
External IDs	OMIM: 601741; MGI: 1922967; HomoloGene: 2597; GeneCards: CUL5; OMA:CUL5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	108,107,761 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	53,581,314 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; glutes; ; muscle of arm; ; biceps brachii; ; triceps brachii muscle; ; deltoid muscle; ; Skeletal muscle tissue of biceps brachii; ; Skeletal muscle tissue of rectus abdominis; ; thoracic diaphragm; ; Epithelium of choroid plexus;
	Top expressed in
	Rostral migratory stream; ; morula; ; tail of embryo; ; zygote; ; spermatid; ; ascending aorta; ; aortic valve; ; spermatocyte; ; muscle of thigh; ; genital tubercle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; ubiquitin protein ligase binding; ubiquitin protein ligase activity; calcium channel activity; ubiquitin-protein transferase activity; signaling receptor activity;
Cellular component	cullin-RING ubiquitin ligase complex; cytosol; Cul5-RING ubiquitin ligase complex; Cul4-RING E3 ubiquitin ligase complex; SCF ubiquitin ligase complex;
Biological process	intrinsic apoptotic signaling pathway; cell population proliferation; ubiquitin-dependent protein catabolic process; negative regulation of cell population proliferation; protein ubiquitination; viral process; ERBB2 signaling pathway; calcium ion transmembrane transport; cellular response to DNA damage stimulus; post-translational protein modification; G1/S transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	8065
	75717
	ENSG00000166266
	ENSMUSG00000032030
	Q93034
	Q9D5V5
	NM_003478
	NM_001161618; NM_027807
	NP_003469
	NP_001155090; NP_082083
	Wikidata
View/Edit Human	View/Edit Mouse

Cullin-5 is a protein that in humans is encoded by the CUL5 gene.