CYFIP2

CYFIP2
Identifiers
Aliases	CYFIP2, PIR121, cytoplasmic FMR1 interacting protein 2, EIEE65, DEE65
External IDs	OMIM: 606323; MGI: 1924134; HomoloGene: 7936; GeneCards: CYFIP2; OMA:CYFIP2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	157,395,595 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	46,203,686 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; middle temporal gyrus; ; saphenous vein; ; lateral nuclear group of thalamus; ; Region I of hippocampus proper; ; Brodmann area 23; ; entorhinal cortex; ; primary visual cortex; ; superior frontal gyrus; ; parietal lobe;
	Top expressed in
	subiculum; ; olfactory tubercle; ; primary motor cortex; ; cerebellar vermis; ; lobe of cerebellum; ; superior colliculus; ; medial dorsal nucleus; ; dorsal tegmental nucleus; ; pontine nuclei; ; primary visual cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; RNA 7-methylguanosine cap binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; neuron projection; cytosol; cell junction; synapse; extracellular exosome; membrane; nucleus; SCAR complex;
Biological process	vascular endothelial growth factor receptor signaling pathway; activation of cysteine-type endopeptidase activity; cell adhesion; Fc-gamma receptor signaling pathway involved in phagocytosis; positive regulation of proteolysis; apoptotic process; neuron projection development; positive regulation of neurotrophin TRK receptor signaling pathway; dendrite extension; cell-cell adhesion; cell morphogenesis; axon guidance; cell projection assembly;
	Sources:Amigo / QuickGO
Orthologs
	26999
	76884
	ENSG00000055163
	ENSMUSG00000020340
	Q96F07
	Q5SQX6
	NM_001037332; NM_001037333; NM_001291721; NM_001291722; NM_014376
	NM_001252459; NM_001252460; NM_133769
	NP_001032410; NP_001278650; NP_001278651; NP_055191
	NP_001239388; NP_001239389; NP_598530
	Wikidata
View/Edit Human	View/Edit Mouse

Cytoplasmic FMR1-interacting protein 2 is a protein that in humans is encoded by the CYFIP2 gene. Cytoplasmic FMR1 interacting protein is a 1253 amino acid long protein and is highly conserved sharing 99% sequence identity to the mouse protein. It is expressed mainly in brain tissues, white blood cells and the kidney.