Cytoglobin

CYGB
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCYGB, HGB, STAP, cytoglobin
External IDsOMIM: 608759; MGI: 2149481; HomoloGene: 12706; GeneCards: CYGB; OMA:CYGB - orthologs
Orthologs
SpeciesHumanMouse
Entrez

114757

114886

Ensembl

ENSG00000161544

ENSMUSG00000020810

UniProt

Q8WWM9

Q9CX80

RefSeq (mRNA)

NM_134268

NM_030206

RefSeq (protein)

NP_599030

NP_084482

Location (UCSC)Chr 17: 76.53 – 76.55 MbChr 11: 116.54 – 116.55 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Cytoglobin is the protein product of CYGB, a human and mammalian gene.

Cytoglobin is a globin molecule ubiquitously expressed in all tissues and most notably utilized in marine mammals. It was discovered in 2001 in hepatic stellate cells during liver fibrosis. Thus, it was originally called "stellate cell activated protein" or STAP. It received its current name in 2002. It is thought to help in the distribution and storage of oxygen as well as protect against hypoxia by scavenging reactive oxygen species . The predicted function of cytoglobin is the facilitation of oxygen among tissues that don't express myoglobin.