CYP1B1

CYP1B1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PM0
Identifiers
Aliases	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1, cytochrome P450 family 1 subfamily B member 1, ASGD6
External IDs	OMIM: 601771; MGI: 88590; HomoloGene: 68035; GeneCards: CYP1B1; OMA:CYP1B1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	38,109,902 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	80,022,490 bp
RNA expression pattern
	Top expressed in
	pericardium; ; cartilage tissue; ; synovial joint; ; trigeminal ganglion; ; spinal ganglia; ; synovial membrane; ; tendon of biceps brachii; ; superficial temporal artery; ; hair follicle; ; urethra;
	Top expressed in
	stroma of bone marrow; ; vestibular membrane of cochlear duct; ; renal corpuscle; ; cumulus cell; ; ciliary body; ; lactiferous gland; ; mesenteric lymph nodes; ; vas deferens; ; ankle joint; ; tunica media of zone of aorta;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	iron ion binding; oxygen binding; metal ion binding; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; oxidoreductase activity; aromatase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; monooxygenase activity;
Cellular component	organelle membrane; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane; endoplasmic reticulum; mitochondrion;
Biological process	toxin metabolic process; steroid metabolic process; retina vasculature development in camera-type eye; cellular response to organic cyclic compound; epoxygenase P450 pathway; endothelial cell-cell adhesion; omega-hydroxylase P450 pathway; angiogenesis; cellular aromatic compound metabolic process; sterol metabolic process; response to toxic substance; visual perception; blood vessel morphogenesis; trabecular meshwork development; negative regulation of NF-kappaB transcription factor activity; regulation of reactive oxygen species metabolic process; retinal metabolic process; endothelial cell migration; nitric oxide biosynthetic process; retinol metabolic process; cell adhesion; negative regulation of cell population proliferation; positive regulation of apoptotic process; positive regulation of receptor signaling pathway via JAK-STAT; negative regulation of cell adhesion mediated by integrin; xenobiotic metabolic process; cellular response to hydrogen peroxide; membrane lipid catabolic process; retinal blood vessel morphogenesis; positive regulation of angiogenesis; positive regulation of vascular endothelial growth factor production; intrinsic apoptotic signaling pathway in response to oxidative stress; arachidonic acid metabolic process; negative regulation of cell migration; estrogen metabolic process; collagen fibril organization;
	Sources:Amigo / QuickGO
Orthologs
	1545
	13078
	ENSG00000138061
	ENSMUSG00000024087
	Q16678
	Q64429
	NM_000104
	NM_009994; NM_001364889
	NP_000095
	NP_034124; NP_001351818
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene.