CatSper2

CATSPER2
Identifiers
Aliases	CATSPER2, CatSper2, cation channel sperm associated 2
External IDs	OMIM: 607249; MGI: 2387404; HomoloGene: 77423; GeneCards: CATSPER2; OMA:CATSPER2 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	43,668,118 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	121,244,273 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; right hemisphere of cerebellum; ; right testis; ; left testis; ; buccal mucosa cell; ; anterior pituitary; ; right uterine tube; ; nipple; ; right frontal lobe; ; right lobe of thyroid gland;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; soleus muscle; ; submandibular gland; ; gastrula; ; primary oocyte; ; neural layer of retina; ; molar; ; ankle;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium activated cation channel activity; calcium channel activity; voltage-gated ion channel activity; ion channel activity; protein binding; voltage-gated sodium channel activity;
Cellular component	integral component of membrane; CatSper complex; cell projection; membrane; plasma membrane; cilium; motile cilium;
Biological process	cell differentiation; membrane depolarization during action potential; regulation of ion transmembrane transport; ion transport; multicellular organism development; calcium ion transmembrane transport; transmembrane transport; spermatogenesis; sperm-egg recognition; calcium ion transport; neuronal action potential; flagellated sperm motility; sodium ion transmembrane transport; fertilization; sperm capacitation; response to progesterone;
	Sources:Amigo / QuickGO
Orthologs
	117155
	212670
	ENSG00000166762
	ENSMUSG00000033486
	Q96P56
	A2ARP9
	NM_001282309; NM_001282310; NM_054020; NM_172095; NM_172097
	NM_153075
	NP_001269238; NP_001269239; NP_742093
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

CatSper2, is a protein which in humans is encoded by the CATSPER2 gene. CatSper2 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca²⁺-permeant ion channel specific essential for the correct function of sperm cells.