Cayuela (surname)
Cayuela is a Spanish surname. Notable people with the surname include:
- Antonio Cayuela (1917–2006), Spanish footballer
 - Aquilino Cayuela (born 1967), Spanish writer, columnist, and professor
 - Emilio Sánchez Cayuela (1907–1993), Spanish painter and draftsman
 - Jorge Cayuela (born 1944), Spanish footballer
 - Javier Cayuela, Spanish sailor
 - Pepe Cayuela (born 1950), Spanish football manager
 - Vicente Maeso Cayuela (1919–1993), Spanish painter and sculptor