Cefotetan

Cefotetan
Clinical data
AHFS/Drugs.com	Consumer Drug Information
Routes of; administration	Injection
ATC code	J01DC05 (WHO) ;
Legal status
Legal status	US: ℞-only;
Identifiers
	IUPAC name (7S)-7-{[4-(1-amino-3-hydroxy-1,3-dioxopropan-2-ylidene); 1,3-dithietane-2-carbonyl]amino}-7-methoxy-; 3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-; 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;
CAS Number	69712-56-7 ;
PubChem CID	53025;
DrugBank	DB01330 ;
ChemSpider	47904 ;
UNII	48SPP0PA9Q;
KEGG	D00260 ;
ChEBI	CHEBI:3499 ;
ChEMBL	ChEMBL474579 ;
CompTox Dashboard (EPA)	DTXSID1022762 ;
ECHA InfoCard	100.067.337
Chemical and physical data
Formula	C17H17N7O8S4
Molar mass	575.60 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1/C(=C(\CS[C@@H]1[C@]2(OC)NC(=O)C3S/C(S3)=C(/C(=O)N)C(=O)O)CSc4nnnn4C)C(=O)O;
	InChI InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1 ; Key:SRZNHPXWXCNNDU-IXOPCIAXSA-N ;
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Cefotetan is an injectable antibiotic of the cephamycin type for prophylaxis and treatment of bacterial infections. It is often grouped together with second-generation cephalosporins and has a similar antibacterial spectrum, but with additional anti-anaerobe coverage.

Cefotetan was developed by Yamanouchi. It is marketed outside Japan by AstraZeneca with the brand names Apatef and Cefotan.

Clinical data

AHFS/Drugs.com	Consumer Drug Information
Routes of administration	Injection
ATC code	J01DC05 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name (7S)-7-{[4-(1-amino-3-hydroxy-1,3-dioxopropan-2-ylidene) 1,3-dithietane-2-carbonyl]amino}-7-methoxy- 3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number	69712-56-7^Y
PubChem CID	53025
DrugBank	DB01330^N
ChemSpider	47904^Y
UNII	48SPP0PA9Q
KEGG	D00260^N
ChEBI	CHEBI:3499^N
ChEMBL	ChEMBL474579^N
CompTox Dashboard (EPA)	DTXSID1022762
ECHA InfoCard	100.067.337
Chemical and physical data
Formula	C₁₇H₁₇N₇O₈S₄
Molar mass	575.60 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C2N1/C(=C(\CS[C@@H]1[C@]2(OC)NC(=O)C3S/C(S3)=C(/C(=O)N)C(=O)O)CSc4nnnn4C)C(=O)O
InChI InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1^Y Key:SRZNHPXWXCNNDU-IXOPCIAXSA-N^Y
^NY (what is this?) (verify)