Cepharanthine

Cepharanthine
Clinical data
Other names	Cepharantin, O-Methylcepharanoline
AHFS/Drugs.com	International Drug Names
ATC code	none;
Identifiers
	IUPAC name (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaene;
CAS Number	481-49-2;
PubChem CID	10206;
ChemSpider	9791;
UNII	7592YJ0J6T;
ChEMBL	ChEMBL449782;
CompTox Dashboard (EPA)	DTXSID6045957 ;
ECHA InfoCard	100.208.632
Chemical and physical data
Formula	C37H38N2O6
Molar mass	606.719 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC2=CC3=C(C4=C2[C@@H]1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)C[C@@H]7C8=CC(=C(C=C8CCN7C)OC)O4)OC)OCO3;
	InChI InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1; Key:YVPXVXANRNDGTA-WDYNHAJCSA-N;

Cepharanthine is an antiinflammatory and antineoplastic compound isolated from Stephania. Due to these modalities, it has been shown effective against HTLV in lab research. Additionally, it has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported.