Syringocystadenoma papilliferum
| Syringocystadenoma papilliferum | |
|---|---|
| Other names | Syringadenoma papilliferum, Fistulous vegetative verrucous hydradenoma, Naevus syringocystadenomatosus papilliferus, Papillary syringocystadenoma, and SCAP. |
| An example of a syringocystadenoma papilliferum | |
| Specialty | Dermatology |
| Usual onset | Childhood, Neonatal, Infancy, Adolescent. |
| Causes | Genetic. |
| Diagnostic method | Skin biopsy. |
| Differential diagnosis | Hidradenoma papilliferum, Papillary eccrine adenoma, Warty dyskeratoma, Tubular apocrine adenoma, Syringocystadenocarcinoma papilliferum. |
| Treatment | Surgical excision. |
Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis.
Lesions have a heterogeneous, non-distinctive appearance that ranges from skin-colored to pink-colored papules or plaques. Typically, lesions form in the head and neck area.
Syringocystadenoma papilliferum can develop de-novo or within a nevus sebaceous. Syringocystadenoma papilliferum tends to be seen in children. It is present at birth in approximately 50% of individuals affected, and it develops before puberty in the remaining 15%-30%.