Cholera toxin
| Cholera toxin Subunit A | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | ctxA | ||||||
| CAS number | |||||||
| NCBI gene | 944742 | ||||||
| PDB | 1S5B | ||||||
| RefSeq | WP_001889387.1 | ||||||
| UniProt | P01555 | ||||||
| Other data | |||||||
| EC number | 2.4.2.36 | ||||||
| Wikidata | Q189245 | ||||||
| |||||||
| Cholera toxin Subunit B | |||||||
|---|---|---|---|---|---|---|---|
3D structure of cholera toxin subunit B. (top view with CTA subunit removed) | |||||||
| Identifiers | |||||||
| Symbol | ctxB | ||||||
| CAS number | |||||||
| NCBI gene | 944741 | ||||||
| PDB | 1CHP | ||||||
| RefSeq | WP_000987577.1 | ||||||
| UniProt | P01556 | ||||||
| Other data | |||||||
| EC number | 2.4.2.36 | ||||||
| Wikidata | Q189245 | ||||||
| |||||||
Cholera toxin (also known as choleragen, CTX, CTx and CT) is a potent enterotoxin produced by the bacterium Vibrio cholerae which causes severe watery diarrhea and dehydration that define cholera infections. The toxin is a member of the heat-labile enterotoxin family, and exists as an AB5 multimeric toxin with one enzymatically active A subunit and five receptor-binding B subunits that facilitate host cell entry.