Christopher Marshall (doctor)
Chris Marshall | |
|---|---|
| Born | Christopher John Marshall 19 January 1949 |
| Died | 8 August 2015 (aged 66) |
| Nationality | British |
| Known for | Work on RAS and RHO family of small GTPases |
| Awards | Fellow of the Royal Society Fellow of the Academy of Medical Sciences Member of European Molecular Biology Organisation Royal Society Buchanan Award Novartis Medal of the Biochemical Society Sterling Medal of the University of Pennsylvania Cancer Research UK Life Time Achievement Award |
| Scientific career | |
| Fields | Cancer Cell biology |
| Institutions | Cancer Research UK Institute of Cancer Research |
Christopher John Marshall FRS FMedSci (19 January 1949 – 8 August 2015) was a British scientist who worked as director of the Division for Cancer Biology at the Institute of Cancer Research. Marshall was distinguished for research in the field of tumour cell signalling. His track record includes the discovery of the N-Ras oncogene , the identification of farnesylation of Ras proteins, and the discovery that Ras signals through the MAPK/ERK pathway. These findings have led to therapeutic development of inhibitors of Ras farnesylation, MEK and B-Raf.