Chromatin structure remodeling (RSC) complex

RSC (Remodeling the Structure of Chromatin) is a protein complex of the ATP-dependent chromatin remodeler family. The activity of the RSC complex allows for chromatin to be remodeled by altering the structure of the nucleosome.

There are four subfamilies of chromatin remodelers: SWI/SNF, INO80, ISW1, and CHD. The RSC complex is a 15-subunit protein complex first discovered in Saccharomyces cerevisiae in 1996, and is homologous to the SWI/SNF complex found in humans. The RSC complex has ATPase activity in the presence of DNA.

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