Chromosome instability syndrome

Chromosome instability syndromes are a group of inherited conditions associated with chromosomal instability and breakage. They often lead to an increased tendency to develop certain types of malignancies.

The following chromosome instability syndromes are known:

• Ataxia telangiectasia
• Ataxia telangiectasia-like disorder
• Bloom syndrome
• Fanconi anaemia
• Nijmegen breakage syndrome