Ciclopirox

Ciclopirox
Above: molecular structure of ciclopirox Below: 3D representation of a ciclopirox molecule
Clinical data
Trade namesPenlac Nail Lacquer, others
Other namesLoprox, CPX
AHFS/Drugs.comMonograph
MedlinePlusa604021
License data
Routes of
administration
Topical
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability<5% with prolonged use
Protein binding94 to 97%
Elimination half-life1.7 hours
Identifiers
  • 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.045.056
Chemical and physical data
FormulaC12H17NO2
Molar mass207.273 g·mol−1
3D model (JSmol)
  • O=C1/C=C(\C=C(/N1O)C2CCCCC2)C
  • InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 Y
  • Key:SCKYRAXSEDYPSA-UHFFFAOYSA-N Y
  (verify)

Ciclopirox is a medication used for the treatment of moderate onychomycosis of fingernails and toenails, and for the treatment of seborrheic dermatitis.

In 2022, it was the 247th most commonly prescribed medication in the United States, with more than 1 million prescriptions.