Ciclotizolam

Ciclotizolam
Clinical data
ATC code	none;
Legal status
Legal status	CA: Schedule IV;
Identifiers
	IUPAC name 8-bromo-6-(o-chlorophenyl)-1-cyclohexyl-4H-5-triazolo(3,4-c)thieno(2,4-e)-1,4-diazepine;
CAS Number	58765-21-2 ;
PubChem CID	71949;
ChemSpider	64956 ;
UNII	JK517QTN4Q;
ChEMBL	ChEMBL2105986 ;
CompTox Dashboard (EPA)	DTXSID40866708 ;
Chemical and physical data
Formula	C20H18BrClN4S
Molar mass	461.81 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc5ccccc5C/2=N/Cc1nnc(n1c3sc(Br)cc\23)C4CCCCC4;
	InChI InChI=1S/C20H18BrClN4S/c21-16-10-14-18(13-8-4-5-9-15(13)22)23-11-17-24-25-19(26(17)20(14)27-16)12-6-2-1-3-7-12/h4-5,8-10,12H,1-3,6-7,11H2 ; Key:ZOSHXIXUCKESEG-UHFFFAOYSA-N ;
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Ciclotizolam (WE-973) is a drug which is a thienotriazolodiazepine derivative. It is a partial agonist for the benzodiazepine site of the GABA_A receptor, with similar binding affinity to related compounds like brotizolam, but a low efficacy.

Clinical data


ATC code	none
Legal status
Legal status	CA: Schedule IV
Identifiers
IUPAC name 8-bromo-6-(o-chlorophenyl)-1-cyclohexyl-4H-5-triazolo(3,4-c)thieno(2,4-e)-1,4-diazepine
CAS Number	58765-21-2^Y
PubChem CID	71949
ChemSpider	64956^Y
UNII	JK517QTN4Q
ChEMBL	ChEMBL2105986^N
CompTox Dashboard (EPA)	DTXSID40866708
Chemical and physical data
Formula	C₂₀H₁₈BrClN₄S
Molar mass	461.81 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc5ccccc5C/2=N/Cc1nnc(n1c3sc(Br)cc\23)C4CCCCC4
InChI InChI=1S/C20H18BrClN4S/c21-16-10-14-18(13-8-4-5-9-15(13)22)23-11-17-24-25-19(26(17)20(14)27-16)12-6-2-1-3-7-12/h4-5,8-10,12H,1-3,6-7,11H2^Y Key:ZOSHXIXUCKESEG-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)