Clotizolam

Clotizolam
Legal status
Legal status	CA: Schedule IV; DE: NpSG (Industrial and scientific use only); UK: Under Psychoactive Substances Act;
Identifiers
	IUPAC name 2-Chloro-4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine;
CAS Number	54123-06-7;
PubChem CID	3041455;
ChemSpider	2304724;
CompTox Dashboard (EPA)	DTXSID50202471 ;
Chemical and physical data
Formula	C15H10Cl2N4S
Molar mass	349.23 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	205 °C (401 °F)
	SMILES CC1=NN=C2N1C3=C(C=C(S3)Cl)C(=NC2)C4=CC=CC=C4Cl;
	InChI InChI=1S/C15H10Cl2N4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)16)10-6-12(17)22-15(10)21(8)13/h2-6H,7H2,1H3; Key:CHGXYVPOFYZWRH-UHFFFAOYSA-N;

Clotizolam (Ro11-1465) is a thienotriazolodiazepine derivative first invented in the 1970s, which in more recent years has been sold as a designer drug. As with other related thienotriazolodiazepines, it produces sedative, anxiolytic, anticonvulsant and muscle relaxant effects, and also acts as an inhibitor of platelet-activating factor (PAF).

Legal status

Legal status	CA: Schedule IV DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act
Identifiers
IUPAC name 2-Chloro-4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
CAS Number	54123-06-7
PubChem CID	3041455
ChemSpider	2304724
CompTox Dashboard (EPA)	DTXSID50202471
Chemical and physical data
Formula	C₁₅H₁₀Cl₂N₄S
Molar mass	349.23 g·mol⁻¹
3D model (JSmol)	Interactive image
Melting point	205 °C (401 °F)
SMILES CC1=NN=C2N1C3=C(C=C(S3)Cl)C(=NC2)C4=CC=CC=C4Cl
InChI InChI=1S/C15H10Cl2N4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)16)10-6-12(17)22-15(10)21(8)13/h2-6H,7H2,1H3 Key:CHGXYVPOFYZWRH-UHFFFAOYSA-N