Food addiction

A food addiction or eating addiction is any behavioral addiction characterized primarily by the compulsive consumption of palatable and hyperpalatable food items, and potentially also sugar-sweetened beverages (SSBs). Such foods often have high sugar, fat, and salt contents (HFSS), and markedly activate the reward system in humans and other animals. Those with eating addictions often overconsume such foods despite the adverse consequences (such as excess weight gain, diabetes, and heart disease) associated with their overconsumption.

Psychological dependence has also been observed, with the occurrence of withdrawal symptoms when substituting foods low in sugar and fat. Professionals address psychological dependence by providing behavior therapy and through administering the YFAS (Yale Food Addiction Scale) questionnaire, a diagnostic criterion of substance dependence.

High-sugar and high-fat foods have been shown to increase the expression of ΔFosB, an addiction biomarker, in the D1-type medium spiny neurons of the nucleus accumbens; however, there is very little research on the synaptic plasticity from compulsive food consumption, a phenomenon which is known to be caused by ΔFosB overexpression.