Concentrative nucleoside transporter
| Nucleos_tra2_C | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Nucleos_tra2_C | ||||||||
| Pfam | PF07662 | ||||||||
| InterPro | IPR011657 | ||||||||
| TCDB | 2.A.41 | ||||||||
| OPM superfamily | 388 | ||||||||
| OPM protein | 3tij | ||||||||
| |||||||||
Human concentrative nucleoside transporters include SLC28A1, SLC28A2 and SLC28A3 proteins. SLC28A2 is a purine-specific Na+-nucleoside cotransporter localised to the bile canalicular membrane. SLC28A1 is a Na+-dependent nucleoside transporter selective for pyrimidine nucleosides and adenosine. It also transports the anti-viral nucleoside analogues Zidovudine and Zalcitabine.