Conjugated linoleic acid

Conjugated linoleic acids (CLA) are a family of isomers of linoleic acid. In principle, 28 isomers are possible. CLA is found mostly in the meat and dairy products derived from ruminants. The two C=C double bonds are conjugated (i.e., separated by a single bond) as opposed by "typical" polyunsaturated fatty acids where double bonds are separated by two single bonds. CLAs are simultaneously both cis-fats and trans-fats, as one of the two C=C bonds is cis and the other trans.

CLA is naturally present in milkfat and beef, has shown some potentially beneficial effects on rodent models of cardiometabolic disease, and is also available as a dietary supplement.