Corkscrew Road
| County Road 850 | |
| Route information | |
| Maintained by Lee County DOT and Collier County TMS | |
| Length | 20.9 mi (33.6 km) |
| Major junctions | |
| West end | US 41 in Estero |
| East end | SR 82 near Immokalee |
| Location | |
| Country | United States |
| State | Florida |
| Counties | Lee, Collier |
| Highway system | |
Corkscrew Road, also designated as County Road 850 (CR 850), is a major road in Southwest Florida running from Estero in Lee County east to a point near Immokalee in Collier County. The western section is the primary east–west road in Estero.