Cupin superfamily
| Cupin_1 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
crystal structure of oxalate decarboxylase formate complex | |||||||||
| Identifiers | |||||||||
| Symbol | Cupin_1 | ||||||||
| Pfam | PF00190 | ||||||||
| Pfam clan | CL0029 | ||||||||
| ECOD | 10.12.1 | ||||||||
| InterPro | IPR006045 | ||||||||
| SCOP2 | 2phl / SCOPe / SUPFAM | ||||||||
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| Cupin_2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
crystal structure of yxag, a dioxygenase from Bacillus subtilis | |||||||||
| Identifiers | |||||||||
| Symbol | Cupin_2 | ||||||||
| Pfam | PF07883 | ||||||||
| Pfam clan | CL0029 | ||||||||
| ECOD | 10.12.1 | ||||||||
| InterPro | IPR013096 | ||||||||
| SCOP2 | 1vj2 / SCOPe / SUPFAM | ||||||||
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| Cupin_3 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
crystal structure of protein ylba from E. coli, pfam duf861 | |||||||||
| Identifiers | |||||||||
| Symbol | Cupin_3 | ||||||||
| Pfam | PF05899 | ||||||||
| Pfam clan | CL0029 | ||||||||
| ECOD | 10.12.1 | ||||||||
| InterPro | IPR008579 | ||||||||
| SCOP2 | 1o5u / SCOPe / SUPFAM | ||||||||
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| Cupin_4 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Cupin_4 | ||||||||
| Pfam | PF08007 | ||||||||
| Pfam clan | CL0029 | ||||||||
| ECOD | 10.12.1 | ||||||||
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| Cupin_5 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
x-ray crystal structure of protein so0799 from Shewanella oneidensis. northeast structural genomics consortium target sor12. | |||||||||
| Identifiers | |||||||||
| Symbol | Cupin_5 | ||||||||
| Pfam | PF06172 | ||||||||
| Pfam clan | CL0029 | ||||||||
| ECOD | 10.12.1 | ||||||||
| InterPro | IPR009327 | ||||||||
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| Cupin_6 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Cupin_6 | ||||||||
| Pfam | PF12852 | ||||||||
| Pfam clan | CL0029 | ||||||||
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| Cupin_7 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Cupin_7 | ||||||||
| Pfam | PF12973 | ||||||||
| Pfam clan | CL0029 | ||||||||
| ECOD | 10.12.1 | ||||||||
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The cupin superfamily is a diverse superfamily of proteins named after its conserved barrel domain (cupa being the Latin term for a small barrel). The superfamily includes a wide variety of enzymes as well as non-enzymatic seed storage proteins.
Members of the superfamily play a role in allergy, especially seed storage proteins like 7S and 11S globulins, also known as vicilins and legumins, respectively. These proteins can be found at high concentrations in seeds of both mono- and dicotyledonous plants and are an important component of the normal human diet.