Cyclopia

Cyclopia
Other namesCyclocephaly, synophthalmia
Fetuses with cyclopia
SpecialtyMedical genetics
Usual onsetDuring embryonic development
DurationLifelong
PrognosisInvariably Fatal
Frequency1 in 100,000 births

Cyclopia (named after the Greek mythology characters cyclopes), also known as alobar holoprosencephaly, is the most extreme form of holoprosencephaly and is a congenital disorder (birth defect) characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses.