Cytochrome b5

Cytochrome b5
Cytochrome B5 (rat) bound to its cofactor. Haem in black, iron in orange and iron-binding histidine residues shown as sticks. (PDB: 1ICC​)
Identifiers
SymbolCYB5A
Alt. symbolsCYB5
NCBI gene1528
HGNC2570
OMIM250790
PDB1JEX
RefSeqNM_001914
UniProtP00167
Other data
LocusChr. 18 q23
Search for
StructuresSwiss-model
DomainsInterPro
Cytochrome b5
Identifiers
SymbolCyt_B5
PfamPF00173
InterProIPR001199
PROSITEPDOC00170
Membranome211
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Cytochromes b5 are ubiquitous electron transport hemoproteins found in animals, plants, fungi and purple phototrophic bacteria. The microsomal and mitochondrial variants are membrane-bound, while bacterial and those from erythrocytes and other animal tissues are water-soluble. The family of cytochrome b5-like proteins includes (besides cytochrome b5 itself) hemoprotein domains covalently associated with other redox domains in flavocytochrome cytochrome b2 (L-lactate dehydrogenase; EC 1.1.2.3), sulfite oxidase (EC 1.8.3.1), plant and fungal nitrate reductases (EC 1.7.1.1, EC 1.7.1.2, EC 1.7.1.3), and plant and fungal cytochrome b5/acyl lipid desaturase fusion proteins.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.